Imaging of Monoclonal Gammapathy of Undetermined Significance and Smoldering Multiple Myeloma
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چکیده
منابع مشابه
Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma.
Monoclonal gammopathy of undetermined significance (MGUS) is characterized by the presence of a serum monoclonal (M) protein level less than 3 g/dL, less than 10% clonal plasma cells in the bone marrow, and the absence of hypercalcemia, renal insufficiency, anemia, or bone lesions attributable to a clonal plasma cell disorder. Patients may be tested for a monoclonal gammopathy by serum protein ...
متن کاملManagement of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM).
Monoclonal gammopathy of undetermined significance (MGUS) is defined as a serum M protein level of less than 3 g/dL, less than 10% clonal plasma cells in the bone marrow, and the absence of end-organ damage. The prevalence of MGUS is 3.2% in the white population but is approximately twice that high in the black population. MGUS may progress to multiple myeloma, AL amyloidosis, Waldenström macro...
متن کاملClinical , Morphological , and Cell Kinetic Differences Among Multiple Myeloma , Monoclonal Gammopathy of Undetermined Significance , and Smoldering Multiple Myeloma
We reviewed the clinical and morphological findings in 43 cases of monoclonal gammopathy of undetermined significance (MGUS). 9 of smoldering multiple myeloma (5MM). and 23 of overt multiple myeloma (MM). In all cases. the patients physicians had requested a bone marrow examination because of the possibility of MM. In all 75 cases. 3H-thymidine labeling indices were performed. The plasma cell l...
متن کاملPathway-based network analysis of myeloma tumors: monoclonal gammopathy of unknown significance, smoldering multiple myeloma, and multiple myeloma.
Although many studies have been carried out on monoclonal gammopathy of unknown significances (MGUS), smoldering multiple myeloma (SMM), and multiple myeloma (MM), their classification and underlying pathogenesis are far from elucidated. To discover the relationships among MGUS, SMM, and MM at the transcriptome level, differentially expressed genes in MGUS, SMM, and MM were identified by the ra...
متن کاملGammopathy of Undetermined Significance to Multiple Myeloma
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ژورنال
عنوان ژورنال: Cancers
سال: 2020
ISSN: 2072-6694
DOI: 10.3390/cancers12020486